منابع مشابه
Hox signals death for neuronal precursors
Hox signals death for neuronal precursors he number of neurons in an adult fly is determined by a death-inducing blast of a homeodomain protein, based on results from When the fly larva hatches, neurons are nearly evenly distributed along the major body axis. But in the adult, they are more numerous in the segments of the thorax than the abdomen, in part because neural stem cells (NSCs) in the ...
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Although Ca(2+) signals are necessary for cell communication and survival, abnormal cellular Ca(2+) load can trigger different cell death programs. Ca(2+) mediates cell death by activating proteases (ie, calpains), by reinforcing signals leading to caspase activation or by triggering other catabolic processes mediated by lipases and nucleases. Failure in the clearance of excitatory amino acid i...
متن کاملCa Signals and Neuronal Death in Brain Ischemia
Although Ca signals are necessary for cell communication and survival, abnormal cellular Ca load can trigger different cell death programs. Ca mediates cell death by activating proteases (ie, calpains), by reinforcing signals leading to caspase activation or by triggering other catabolic processes mediated by lipases and nucleases. Failure in the clearance of excitatory amino acid is a critical...
متن کاملExtracellular signals that regulate the tangential migration of olfactory bulb neuronal precursors: inducers, inhibitors, and repellents.
Neuronal migration is an essential developmental step in the construction of the vertebrate nervous system, but the extracellular signals involved in initiating and regulating neuronal movement remain unclear. Here we report the identification of a novel astrocyte-derived migration-inducing activity (MIA). Using an in vitro assay, we show that MIA induces the migration of olfactory bulb interne...
متن کاملPrecursors of Sudden Coronary Death
Precursors of sudden death were sought in men 1838 civil servants in Albany, New York, and 2282 residents of Framingham, Massachusetts under continuous surveillance for 16 years. In men 45-74 years old there were 234 deaths attributed to coronary heart disease (CHD) of which 109 occurred within one hour of onset of symptoms. More than half of all deaths due to CHD occurred outside the hospital ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2003
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1604rr1